Search on: BETA 2 MICROGLOBULIN 
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Descriptor English:   beta 2-Microglobulin 
Descriptor Spanish:   Microglobulina-2 beta 
Descriptor Portuguese:   Microglobulina-2 beta 
Synonyms English:   2-Microglobulin, beta
beta 2 Microglobulin
Thymotaxin  
Tree Number:   D12.776.124.790.223.100
D12.776.377.715.182.100
Definition English:   An 11-kDa protein associated with the outer membrane of many cells including lymphocytes. It is the small subunit of the MHC class I molecule. Association with beta 2-microglobulin is generally required for the transport of class I heavy chains from the endoplasmic reticulum to the cell surface. Beta 2-microglobulin is present in small amounts in serum, csf, and urine of normal people, and to a much greater degree in the urine and plasma of patients with tubular proteinemia, renal failure, or kidney transplants. 
Indexing Annotation English:   /biosyn /physiol /blood permitted
History Note English:   91(75); was BETA 2 MICROGLOBULIN 1984-90; was see under BETA GLOBULINS 1975-83 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification CT contraindications
DF deficiency DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects SE secretion
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   29233 
Unique Identifier:   D001613 

Occurrence in VHL:
 

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